The Common Vein Copyright 2010
Definition
Premenstrual Disorder or Syndrome (PMS) is a group of systemic and local manifestations of the late phase (luteal or proliferative) part of the cycle thought to be caused by abnormal sensitivity to the fluctuation of estrogen and progesterone levels, serotonin deficiency, magnesium or calcium deficiency resulting in by physical psychological and behavioral changes.
Clinically symptoms occur a few days prior to menstruation and can involve abdominal and pelvic pain as well as mood changes. Mood changes include irritability, anxiety and depression. Physical symptoms can include bloating/fluid retention, breast tenderness, headaches, and muscle or joint pain.
The treatment of PMS frequently requires a multidisciplinary approach including medical and non medical treatments. Non medical approaches include emphasizing regular exercise and adequate nutrition and sleep. Medical management includes SSRI (selective serotonin re-uptake inhibitor) and antidepressants.